Immunostimulant Effect Test Of Curcuminoid Extract From Turmeric Rhizome (Curcuma Domestica Val.) In VCO On Rats Induced Cyclophosphamide Againts An Increasing Total Leukocytes And Leukocyte Differential

Turmeric (Curcuma domestica Val.) is a traditional Indonesian plant that has many benefits. Curcuminoids are turmeric compounds known to have effects as immunomodulators and been proven in several vivo tests. Immunosuppressive drugs such cyclophosphamide widely given improve clinical symptoms autoimmune patients cancer treatment which can cause susceptibility infection.Therefore,this study aimed determine the immunostimulating effect of curcuminoid extract from rhizome on cyclophosphamide-induced white rats. Proof extracts was by testing total leukocytes leukocytesdifferential. The test results showed 1 mL, 0.5 0.25 mL increased leukocyte differential (lymphocytes, neutrophils, monocytes, basophils, eosinophils) with significant difference (p<0.05) Na group CMC 0.5% negative control. Therefore, had potential an immunostimulant.
 immunostimulant.